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Media and Research Publications About TMS In Depression


Media and Research Publications About TMS In Depression

The latest: ABC7 News covers a new study at UCLA, already showing promising results, that uses TMS to see if administering mild electrical currents into the brain can reset its networks for those dealing with post-traumatic stress disorder.
Contemporary perspectives on neuromodulation are summed up in a recent review from our group (Cook, et al., 2014), which also discusses some of the innovations in neuromodulation from UCLA (e.g., sTMS and TNS). As well, we have proposed a new theoretical framework for understanding the mechanisms of action for various forms of magnetic stimulation (Leuchter, et al., 2013)
Many research studies over the past two decades have examined the use of transcranial magnetic stimulation in the management of depression. The early TMS studies contributed important infomation about aspects of effective dose, stimulation parameters, safety, and tolerability. The meta-analytic review paper by Gross and colleagues (2007) helps summarize much of this work, as does the report from Slotema and colleagues (2010).
The papers by O'Reardon, et al. (2007), Janicak, et al. (2008), Avery, et al. (2008), and Lisanby, et al. (2009) present findings from pivotal registration trial for the Neuronetics NeuroStar system, while that from George, et al. (2010) presents findings from the independent NIH-funded OPT-TMS trial. The report from Janicak, et al. (2010) addresses questions of durability of response.
We participated in a multi-site clinical trial that addressed outcomes with real-world, care-seeking patients in a clinically-directed TMS treatment protocol (Carpenter, et al., 2012; Janicak, et al., 2013).
Gross2007">Gross M, Nakamura L, Pascual-Leone A, Fregni F. "Has repetitive transcranial magnetic stimulation (rTMS) treatment for depression improved? A systematic review and meta-analysis comparing the recent vs. the earlier rTMS studies." Acta Psychiatr Scand. 2007 Sep; 116(3):165-73. abstract
O'Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald PB, Loo C, Demitrack MA, George MS, Sackeim HA. "Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial." Biol Psychiatry. 2007 Dec 1; 62(11):1208-16. abstract
Janicak PG, O'Reardon JP, Sampson SM, Husain MM, Lisanby SH, Rado JT, Heart KL, Demitrack MA. "Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatment." J Clin Psychiatry. 2008 Feb; 69(2):222-32. abstract
Avery2008">Avery DH, Isenberg KE, Sampson SM, Janicak PG, Lisanby SH, Maixner DF, Loo C, Thase ME, Demitrack MA, George MS. "Transcranial magnetic stimulation in the acute treatment of major depressive disorder: clinical response in an open-label extension trial." J Clin Psychiatry. 2008 Mar; 69(3):441-51. abstract
Lisanby2009">Lisanby SH, Husain MM, Rosenquist PB, Maixner D, Gutierrez R, Krystal A, Gilmer W, Marangell LB, Aaronson S, Daskalakis ZJ, Canterbury R, Richelson E, Sackeim HA, George MS. "Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: clinical predictors of outcome in a multisite, randomized controlled clinical trial." Neuropsychopharmacology. 2009 Jan; 34(2):522-34. abstract
Janicak2010">Janicak PG, Nahas Z, Lisanby SH, Solvason HB, Sampson SM, McDonald WM, Marangell LB, Rosenquist P, McCall WV, Kimball J, O'Reardon JP, Loo C, Husain MH, Krystal A, Gilmer W, Dowd SM, Demitrack MA, Schatzberg AF. "Durability of clinical benefit with transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant major depression: assessment of relapse during a 6-month, multisite, open-label study." Brain Stimul. 2010 Oct; 3(4):187-99. abstract
George2010">George MS, Lisanby SH, Avery D, McDonald WM, Durkalski V, Pavlicova M, Anderson B, Nahas Z, Bulow P, Zarkowski P, Holtzheimer PE 3rd, Schwartz T, Sackeim HA. "Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial. " Arch Gen Psychiatry. 2010 May;67(5):507-16. abstract
Slotema2010">Slotema CW, Blom JD, Hoek HW, Sommer IE. "Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders. " J Clin Psychiatry. 2010 Jul;71(7):873-84. abstract
Carpenter2012">Carpenter LL, Janicak PG, Aaronson ST, Boyadjis T, Brock DG, Cook IA, Dunner DL, Lanocha K, Solvason HB, Demitrack MA. "Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice." Depress Anxiety. 2012 Jul;29(7):587-96. abstract
Janicak2013">Janicak PG, Dunner DL, Aaronson ST, Carpenter LL, Boyadjis TA, Brock DG, Cook IA, Lanocha K, Solvason HB, Bonneh-Barkay D, Demitrack MA. "Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of quality of life outcome measures in clinical practice." CNS Spectr. 2013 Dec;18(6):322-32. abstract
Leuchter2013">Leuchter AF, Cook IA, Jin Y, Phillips B. "The relationship between brain oscillatory activity and therapeutic effectiveness of transcranial magnetic stimulation in the treatment of major depressive disorder." Front Hum Neurosci. 2013 Feb 26;7:37. abstract
Cook2014">Cook IA, Espinoza R, Leuchter AF. "Neuromodulation for depression: invasive and noninvasive (deep brain stimulation, transcranial magnetic stimulation, trigeminal nerve stimulation)." Neurosurg Clin N Am. 2014 Jan;25(1):103-16. abstract